Mail:
Department of Psychology
415 Campbell Hall
University of Birmingham at Alabama
Birmingham, AL 35226

Phone: 205-934-3850
Fax: 205-975-6110
Email: boggiano@uab.edu

 

 

Dr. Mary M. Boggiano
(formerly M. M. Hagan)

Associate Professor

 

 

EDUCATION:

Graduate: University of Texas at El Paso, Psychobiology, Ph. D., 1998
Postgraduate: University of Cincinnati Medical College, Dept. of Psychiatry,
Behavioral Neuroendocrinology, 1998-2000


MEMBER OF
:

Society for Neuroscience (SFN)
European Brain Research Association
International Behavioral Neuroscience Society (IBNS)
Society for the Study of Ingestive Behavior (SSIB)
Academy for Eating Disorders (AED)
International Behavioral Neuroscience Society (IBNS)
International Union of Physiological Sciences (IUPS)
National Eating Disorders Association (NEDA)
North American Association for the Study of Obesity (NAASO)
National Hispanic Science Network on Drug Abuse (NHSN)
Binge Eating Disorder Association (BEDA)


RESEARCH INTERESTS:

Areas of research include the development of animal models of eating non-homeostatic eating (e.g.,
bulimia nervosa, binge-eating, and obesity). These are based on interactions between environmental
 factors including a history of dieting (via cyclic caloric-restriction-refeeding), stress, access to highly
 palatable food, and non-food cues associated with overeating. These interactions have been found to
alter the brain’s opioid control of food reward and to alter stress hormone responses. Other systems
studied are brain monoamine, PYY, and melanocortin hormones in control of hunger, satiety and
 reward. More recently, research involves translation of discovered abnormalities in the rat models to
understand and validate the concept of “food addiction” in humans. For this, new pharmacological
challenges targeting opioid and stress hormone abnormalities and SNP gene mapping is being utilized
to find biomarkers of (or predictors) of food addiction.

 



CURRENT  PROJECTS:

-Neuroendocrine and genetic markers of food addiction in humans.
-Food addiction in Americans sequestered from U.S.-typical diet in Fiji.
-Meal patterns associated with high BMIs: a survey to shape behavior into long-term weight loss.
- Quantification of concocting phenomena in human binge-eating.


RESEARCH ADVOCACY ACTIVITY
:

-National Institute of Mental Health (NIMH) Division of Pediatric Translational Research and Treatment Development, “Strategies to increase research in the early recognition of eating disorders in children and adolescents", Bethesda, MD, 2004

-American Psychological Association (APA) Science Policy Office, “Value of basic research funding” advocacy to U.S. Congressional staff, Washington, DC, 2005.

-ABC News – online commentator for breaking pre-press medical releases.

-Member of the Research Committee for National Eating Disorders Association (NEDA), 2008-present.

-Scientific Advisory Council: Binge Eating Disorders Association (BEDA), 2010-present.

-DSM-V Task Force on the official classification of Binge-Eating Disorder



SELECTED PUBLICATIONS:

Hagan, M. M., & Moss, D. E. (1991). An animal model of bulimia nervosa: opioid sensitivity to fasting episodes. Pharmacology, Biochemistry & Behavior, 39, 421- 422.

Hagan, M. M., & Moss, D. E. (1993). The effect of naloxone and antidepressants on hyperphagia produced by peptide YY. Pharmacology, Biochemistry &Behavior, 45, 941-944.

Hagan, M. M., & Moss, D. E. (1993). Suppression of peptide YY-induced hyperphagia by terbutaline. Pharmacology, Biochemistry & Behavior, 46, 679-681.

Hagan, M. M., & Moss, D. E. (1994). Differential effects of Tyr-MIF-1, MIF-1, and naloxone on peptide YY-induced hyperphagia. Peptides, 15, 243-245.

Hagan, M. M., & Moss, D. E. (1995). Effect of peptide YY (PYY) on food-associated conflict. Physiology & Behavior, 58, 731-735.

Hagan, M. M., & Moss, D. E. (1997). Persistence of binge-eating patterns after a history of restriction with intermittent bouts of refeeding on palatable food in rats: Implications for bulimia nervosa. International Journal of Eating Disorders, 22, 411-420.

Hagan, M. M., Holguin, F., Cabello C. E., Hascomb, D., & Moss, D. E. (1997). Combined naloxone and fluoxetine on deprivation-induced binge-eating of palatable foods in rats. Pharmacology, Biochemistry & Behavior, 58, 1103-1107.

Hagan, M. M., Castañeda, E., Fleming, S. M., Sumaya-Smith, I., Galloway, J., & Moss, D. E. (1998). Effect of peptide YY (PYY)-induced eating and drinking on the in vivo release of hippocampal acetylcholine (ACh), Brain Research, 805, 20-28.

Hagan, M. M., Rushing, P. A., Schwartz, M. W., Yagaloff, K. A., Burn, P., Woods, S.C.,& Seeley, R. J. (1999). Role of CNS melanocortin system in response to overfeeding. Journal of Neuroscience, 19, 2362-2367.

Hagan, M. M., Havel, P. J., Seeley, R. J., Woods, S. C., Ekhator, N. N., Baker, D. G., Hill, K. K., Wortman, M. D., Miller, A. H., Gingerich, R. L., & Geracioti, T. D. (1999). Cerebrospinal fluid leptin measurements: Covariability with dopamine and cortisol in fasting humans. Journal of Clinical Endocrinology & Metabolism, 84, 3579-2558.

Hagan, M. M., Whitworth, R. H., & Moss, D. E. (1999). Semistarvation-associated eating behaviors among college binge-eaters: A preliminary description and assessment scale. Behavioral Medicine, 25, 125-133.

Hagan, M. M., Tomaka, J., & Moss, D. E. (1999). Relation of dieting in college and high school students to symptoms associated with semistarvation. Journal of Health Psychology, 5, 7-15.

Hagan, M. M., Rushing, P.A., Pritchard, L. M. Schwartz, M. W., Strack, A., Vander Ploeg, L., Woods, S.C. & Seeley, R. J. (2000). Long-term orexigenic effects of agouti related peptide (83-132) involve mechanisms other than melanocortin receptor blockade. American Journal of Physiology ,279, R47-R52.

Hagan, M. M., Rushing, P. A., Benoit, S. C., Woods, S. C., & Seeley, R. J. (2001). Opioid receptor involvement in the effect of AgRP(83-132) on food intake and food selection. American Journal of Physiology, 280: R814-R821.

Hagan, M. M., Benoit, S. C., Rushing, P. A., Pritchard, L. M., Woods, S. C., & Seeley, R.J. (2001). Immediate and prolonged patterns of AgRP (83-132)-induced c-Fos activation in hypothalamic and extrahypothalamic sites. Endocrinology, 142 (3), 1050-1056.

Hagan, M. M.  (2002).  Peptide YY:  A key mediator of orexigenic behavior.  Peptides, 23,  377-382.

Hagan, M. M., Wauford, P. K., Chandler, P. C., Jarrett, L. A., Rybak, R. J., & Blackburn, K. (2002). A new animal model of binge eating: key synergistic role of past caloric restriction and stress. Physiology & Behavior,77, 45-54.

Hagan, M. M., Shuman, E. S., Oswald, K. D., Corcoran, K. J., Profitt, J. H., Blackburn, K. Schwiebert, M. W., Chandler, P.C., Birbaum, C.  (2002). Incidence of Chaotic Eating Behaviors in Binge-Eating Disorder: Contributing Factors.  Behavioral Medicine, 28, 99-105.

Hagan, M. M., Chandler, P. C., Wauford, P. K., Rybak, R. J., & Oswald, K. D.  (2003).  The role of palatable food and hunger as trigger factors in an animal model of stress-induced binge-eating.  International Journal of Eating Disorders, 34,183-197.

Hagan, M. M., Chandler, P. C., Wauford, P. K.  (2003).  The CNS melanocortin system: a biological weapon against the threat of obesity.  Current Medicinal Chemistry Central Nervous System Agents, 3, 201-215.

Chandler, P. C., Oswald, K. D., Maldonado, C., Wauford, P. K., Placidi, R. J. & Hagan, M. M. (2004).  Effect of cholecystokinin (CCK-8) on hyperphagia induced by a high-fat diet and melanocortin antagonism, Peptides,25, 299-306.

Placidi, R. J., Chandler, P. C., Oswald, K. D., Maldonado, C., Wauford, P. K. & Boggiano, M. M.  Stress and hunger alter the anorectic efficacy of fluoxetine on the binge-eating of rats with a history of caloric restriction, International Journal of Eating Disorders ,36, 1-14. 

Tschop, M., Castaneda, T. R., Joost, H. G., Thone-Reineke, C., Ortmann, S., Klaus, S., Hagan, M. M., Chandler, P. C., Oswald, K. D., Benoit, S. C., Seeley, R. J., Kinzig, K.P., Moran, T. H., Beck-sickinger, A.G., Koglin, N., Rodgers, R.J., Blundell, J.E., Ishii, Y., Beattie, A.H., Holch, P., Allison, D. B., Raun, K., Madsen, K., Wulff, B.S., Stidsen, C.E., Birringer, M., Kreuzer, O. J., Schindler, M., Arndt, K., Rudolf, K., Mark, M., Deng, X.Y., Withcomb, D.C., Halem, H., Taylor, J., Dong, J., Datta, R., Culler, M., Craney, S., Flora, D., Smiley, D., Heiman, M. L. (2004).  Physiology: does gut hormone PYY3-36 decrease food intake in rodents?  Nature, 430 (6996): pg. 1-2 following 165.

Chandler, P. C., Viana, J. B., Oswald, K. D., Wauford, P. K., & Boggiano, M. M. (2005). Feeding response to melanocortin agonist predicts preference for and obesity from a high-fat diet. Physiology & Behavior, 85, 221-230.

Boggiano, M. M., Chandler, P.C., Oswald, K.D., Rodgers, R.J., Blundell, J.E., Ishii, Y., Beattie, A.H., Holch, P., Allison, D. B., Schindler, M., Arndt, K., Rudolf, K., Mark, M., Schölch, C., Joost, H. G., Klaus, S., Thöne-Reineke, C., Benoit, S.C., Seeley, R.J., Beck-Sickinger, A.G., Koglin, N., Raun, K., Madsen, K., Wulff, B. S., Stidsen, C.E., Birringer, M., Kreuzer, O. J., Deng, X. Y., Withcomb, D.C., Halem, H., Taylor, J., Dong, J., Datta, R., Culler, M., Ortmann, S., Castañeda, T.R., & Tschöp, M. (2005). PYY3-36 as an anti-obesity target. Obesity Reviews, 6, 307-322.

Boggiano, M. M., Chandler, P. C., Viana, J. B., Oswald, K. D., Maldonado, C. R., &
Wauford, P. K. (2005). Combined dieting and stress evoke exaggerated responses to opioids in binge-eating rats. Behavioral Neuroscience, 119, 1207-1214.

Keith, S., Redden, D. T., Katzmarzyk, P., Boggiano, M. M., Hanlon, E. C., Benca, R.M., Ruden, D., Pietrobelli, A., Barger, J., Fontaine, K., Wang, C., Aronne, L., Wright, S., Baskin, M., Dhurandhar, N., Lijoi , M.C., Grilo, C., Deluca, M., Westfall, A. O. & Allison, D. B. (2006). Putative contributors to the secular increase in obesity: Exploring the roads less traveled. International Journal of Obesity, 30, 1585-94.

Boggiano, M. M. & Chandler, P. C. (2006). Binge-eating in rats produced by combining dieting with stress. Ch. 9: Animal Models of Neurologic and Psychiatric Disease, Current Protocols in Neuroscience, 9.23A1 – 9.23A.8.

Chandler, P.C., Castaneda, E., Viana, J.B., Oswald, K.D., Maldonado, C., & Boggiano, M.M. (2007). A history of human-like dieting alters serotonergic control of feeding and neurochemical balance in a rat model of binge-eating. International Journal of Eating Disorders, 40: 136-142.

Boggiano, M. M., Artiga, A. I., Pritchett, C. E., Chandler, P.C., Smith, M. L., & Eldridge, A. J.  (2007). High intake of palatable food predicts binge-eating characteristics independent of susceptibility to obesity: An animal model of lean vs. obese binge eating and obesity with and without binge-eating. International Journal of Obesity, 31:1357-67.

Artiga, A. I., Viana, J. B., Maldonado, C.R., Chandler-Laney, P. C., Oswald, K. D. &  Boggiano, M. M.  (2007). Body composition and endocrine status of long-term stress-induced binge-eating rats.  Physiology & Behavior,91, 424-431.

Chandler-Laney, P.C., Castaneda, E., Artiga, A.I., Eldridge, A., Maddox, L., & Boggiano, M. M. (2007).  History of caloric restriction induces neurochemical and behavioral changes in rats consistent with models of depression.  Pharmacology, Biochemistry and Behavior, 87: 104–114.

Boggiano, M. M., Cavigelli, S. A., Dorsey, J. R., Pritchett-Kelley, C. E., Ragan, C.M., & Chandler-Laney, P. C. (2008). Effect of a cage divider permitting social stimuli on stress and food intake in rats. Physiology & Behavior,95, 222-228.

McAllister, E. J., Dhurandhar, N. V., Keith, S., Aronne, L. J., Barger, J. , Baskin, M., Benca, R. M., Biggio, J., Boggiano, M. M., Eisenmann, J. C., Elobeid, M. , Fontaine, K., Gluckman, P., Hanlon, E. C., Katzmarzyk, P., Pietrobelli, A., Redden, D. T., Ruden, D. , Wang, C., Waterland, R., Wright, S., & Allison, D. B. (2009). Ten putative contributors to the obesity epidemic. Critical Reviews in Food Science and Nutrition. 49, 868-913.

Boggiano, M.M., Dorsey, J., Thomas, J. M., & Murdaugh, D. (2009). The Pavlovian power of palatable food: lessons for weight-loss adherence from a new rodent model of cue-induced overeating. International Journal of Obesity, 33: 693-701.

Oswald, K. D., Murdaugh, L. D., King, L. V. & Boggiano, M.M. (2010). Motivation for palatable food despite consequences in an animal model of binge-eating. International Journal of Eating Disorders,epub ahead of print.


COURSES CURRENTLY TEACHING:


PY101 - Intro to Psychology
PY335 - Motivation & Emotion
PY455/791 - Psychology of Eating Disorders
PY 710 - Integrative Neuroscience


TEACHING AWARDS


-Professor of the Month Award - Alpha Omicron Pi (UAB), 2002
-Who’s Who Among America’s Teachers (Student Nominated), 2003
-Academic Keys Who's Who in Social Sciences Higher Education, 2004
-Selection to UAB -Master Teacher Program, 2005
-President’s Award for Excellence in Teaching (UAB School of Social & Behavioral Sciences), 2006
-Professor of the Month Award – Alpha Omicron Pi (UAB), 2007
-Professor of the Month Award – Alpha Omicron Pi (UAB), 2010


LAB STUDENT AWARDS

Paula Chandler -  Behavioral Neuroscience Ph.D. Program
-1st Place Winner of Graduate Student Research Competition, 2003
-Recipient of WIN (Women In Neuroscience) Award, SFN, 2003
-Outstanding Graduate Student in Behavioral Neuroscience, 2005
-Overall Outstanding Graduate Student in Psychology, 2005
-Winner of the Social & Behavioral Sciences Dean’s Graduate Research Award, 2005
-Winner of the Samuel B. Barker Award for Excellence in Graduate Studies
-Recipient of SSIB (Society for the Study of Ingestive Behavior) Travel Award, 2005
-2006 Science Unbound Foundation Award for Best Paper in the Area of Obesity or Nutrition


Pamela Wauford -  Undergraduate Psychology Honors Program
-1st Place Winner in W. P. Ost Research Competition, 2002

Kim Oswald - Undergraduate Psychology Honors Program
-2nd Place Winner of W. P. Ost Research Competition, 2003
-Academy for Eating DisordersJunior Research Travel Award, 2003


Jason Viana - Undergraduate Psychology Honors Program
-Winner of the Outstanding Psychology Student, 2004
-Winner of the Passey Prize, 2004


Annie Artiga - Undergraduate Psychology Honors & McNair Scholar Program
-3rd Place Winner, UAB Summer Research Intern Poster Session, 2004
-1st Place Winner, W. P. Ost Research Competition, 2005
-Honorable Mention,UAB Summer Research Intern Poster Session, 2005 -Winner of the Outstanding Psychology Student, 2006
-Winner of the Passey Prize, 2006
-Dean's Award for the Outstanding Undergraduate Student in Social & Behavioral Science, 2006

Jamie Dorsey - Undergraduate Psychology Honor’s Program
-1st Place Award, Oral Presentations, 5th Annual Troy University Psychology Conference, 2007

Donna Murdaugh - Undergraduate Psychology Honors Program
-1st Place Award, Oral Presentation in Social Sciences, Alabama Systems Honors Research Competition, 2007

Vinetra KingRamsey High School, CORD Program
-2nd Place Award, Summer Science Institute Competition, 2007
-2nd Place Award, The Central Alabama Regional Science& Engineering Fair, 2008


FOR INFORMATION ON EATING DISORDERS:
http://www.nationaleatingdisorders.org
http://www.anad.org
http://www.nimh.nih.gov/publicat/eatingdisorders
http://aedweb.org
http://www.edreferral.com
http://www.bedaonline.com



FOR INFORMATION ON HEALTHY WEIGHT-LOSS:
http://www.oa.org
http://www.mypyramid.gov
http://win.niddk.nih.gov/publications/index.htm
http://rosedogbookstore.com/plsyacoha.html
http://www.magnolia-creek.com
http://www.acenterforeatingdisorders.com


FOR EATING DISORDER SUPPORT GROUPS & TREATMENT CENTERS:
http://www.oa.org
foodegrams@gmail.com
http://www.healthyplace.com/Communities/Eating_Disorders/Site/comm_calender.htm
http://www.magnolia-creek.com
http://www.acenterforeatingdisorders.com