Email to:

knightdc@uab.edu

Dr. David Knight

Assistant Professor

EDUCATION
:

B.S. in Psychology, Truman State University (1994)
M.S. in Psychology, University of Wisconsin-Milwaukee (1999)
Neuropsychology Internship, West Virginia University School of Medicine (2001-2002)
Ph.D. in Psychology, University of Wisconsin-Milwaukee (2002)
Postdoctoral Fellowship, National Institute of Mental Health (2002-2007)


RESEARCH PROGRAM:

This research is focused on better understanding the neural systems mediating human learning, memory, and emotion. Behavioral and functional MRI studies from this laboratory investigate the acquisition, expression, and extinction of human Pavlovian fear conditioning. We are interested in the role of awareness in the expression of fear-related behaviors, the neural circuitry mediating aware and unaware fear memory processes, and brain regions that process properties of fearful stimuli compared to regions that produce behavioral and autonomic fear responses.


REPRESENTATIVE PUBLICATIONS:

Knight, D. C., Smith, C. N., Stein, E. A., & Helmstetter, F. J. (1999). Functional MRI of human Pavlovian fear conditioning: Patterns of activation as a function of learning. NeuroReport, 10 (17), 3665-3670.

Cheng, D. T., Knight, D. C., Smith, C. N., Stein, E. A., & Helmstetter, F. J. (2003). Functional MRI of human amygdala activity during Pavlovian fear conditioning: Stimulus processing versus response expression. Behavioral Neuroscience, 117 (1), 3-10.

Knight, D. C., Nguyen, H. T., & Bandettini, P. A. (2003). Expression of conditional fear with and without awareness. Proceedings of the National Academy of Sciences, 100 (25), 15280-15283.

Knight, D. C., Cheng, D. T., Smith, C. N., Stein, E. A., & Helmstetter, F. J. (2004). Neural substrates mediating human delay and trace fear conditioning. Journal of Neuroscience, 24 (1), 218-228.

Knight, D. C., Smith, C. N., Cheng, D. T., Stein, E. A., & Helmstetter, F. J. (2004). Amygdala and hippocampal activity during acquisition and extinction of human fear conditioning. Cognitive, Affective, and Behavioral Neuroscience, 4 (3), 317-325.

Haut, M., Kuwabara, H., Leach, S., Moran, M., Arias, R., Knight, D. (2005). The effect of education on age-related functional activation during working memory. Aging, Neuropsychology, and Cognition, 12, 216-229.

Knight, D. C., Nguyen, H. T., & Bandettini, P. A. (2005). The role of the human amygdala in the production of conditioned fear responses. NeuroImage, 26, 1193-1200.

Knight, D. C., Nguyen, H. T., & Bandettini, P. A. (2006). The role of awareness in delay and trace fear conditioning in humans. Cognitive, Affective, and Behavioral Neuroscience, 5 (2), 157-162.

Cheng, D. T., Knight, D. C., Smith, C. N., Stein, E. A., & Helmstetter, F. J. (2006). Human amygdala activity during the expression of fear responses. Behavioral Neuroscience, 120 (6), 1187-1195.

Dunsmoor, J. E., Bandettini, P. A., & Knight, D. C. (In Press). Impact of continuous versus intermittent CS-UCS pairing on human brain activation. Behavioral Neuroscience.

Knight, D. C. Waters, N. S., & Bandettini, P. A. (Submitted). Distinguishing the neural substrates of declarative and nondeclarative fear memory.

Smith, C. N., Knight, D. C., Cheng, D. T., McIntosh, A. R., Chau, W. K., Stein, E. A., & Helmstetter, F. J. (In Progress). Acquisition and reversal of differential fear conditioning in humans using fMRI.
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